The TCR is a member of the immunoglobulin superfamily, a large group of proteins involved in binding, recognition, and adhesion; the family is named after antibodies (also called immunoglobulins).

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The TCR (T-cell receptor) is a complex of integral membrane proteins that participate in the activation of T-cells in response to an antigen. Stimulation of TCR is triggered by MHC (major histocompatibility …

Dec 13, 2021 · Normal T cell development in the thymus undergoes a major developmental checkpoint in which T cell receptor (TCR) signaling is involved.

3 days ago · T Cell Receptor (TCR) activation promotes a number of signaling cascades that ultimately determine cell fate through regulating cytokine production, cell survival, proliferation, and differentiation.

Another type of immunotherapy that is currently showing promise is T-cell receptor (TCR) therapy. Like CAR-T cell therapy, TCR therapy involves the modification of T cells in a lab.

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Welcome to the T cell receptor (TCR) structural repertoire database. Here we provide an easy-to-use interface to view all experimentally determined structures of T cell receptors and their complexes.

T cell receptor (TCR) therapy is a new type of treatment that uses your own immune cells to fight cancer. It is a promising therapy for some types of cancer, including soft tissue sarcoma.

Discover the role played by T cell receptors (TCR) in cell-mediated immune defence. Overview of TCR activation, signalling, development and diversity and T cell mediated therapies are discussed.