Cell-penetrating peptides (CPPs) are short peptides that facilitate cellular intake and uptake of molecules ranging from nanosize particles to small chemical compounds to large fragments of …

We also present the current state of knowledge about the molecular mechanisms of cell penetration, the various strategies for designing cell-permeable, biologically active cyclic …

Cell-penetrating peptides are promising agents for disease diagnosis and therapy because they can drive cell- and tissue-specific internalization of diagnostic labels and therapeutics into live …

Sep 1, 2023 · To support efficient cell entry and to bypass the problem of poor cellular uptake, cell-penetrating peptides (CPPs) came into the focus of research as valuable drug delivery tools.

Feb 28, 2025 · The team devised and patented a cell-permeable peptide derived from G3BP1, which they found dissolves these granules and ramps up the production of new proteins …

Jun 23, 2021 · Cell-Permeable Peptides (CPPs) are short peptides that are able to pass the cell membrane. CPPs have found use for transporting cargo molecules as fluorophores, drugs, …

Broadly speaking, researchers have been pursuing two different strategies to design cell-permeable cyclic peptides, corresponding to two different cellular entry mechanisms: passive …

Mar 17, 2023 · A comprehensive membrane permeability database is essential for developing computational methods for cyclic peptide drug design. In this study, we constructed …

Mar 25, 2022 · Cell-penetrating peptides (CPPs) and blood-brain barrier-penetrating peptides (B3PPs) have been explored by the biotechnological and pharmaceutical industries to develop …

Jun 1, 2023 · Naturally occurring cell-penetrating peptides exploit direct translocation, endocytosis, and passive diffusion for cell permeability (reviewed in Ref. [8]). The underlying …