Evidence from multiple model systems supports a shift away from heme transport and toward metabolic dysfunction and oxidative stress as key drivers of TANGO2 deficiency.

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

A doping strategy is reported to break the electronic symmetry of catalytic sites for cyclohexanone oxime electrosynthesis from NO and cyclohexanone. Ampere-level electrosynthesis of cyclohexanone ...