Researchers have identified adaptive traits in cancer cells that help tumors resist immunotherapy drugs after extended targeted treatment, revealing new hurdles to effective cancer treatment. A ...

Mass spectrometry reveals protein acetylation to be as widespread as phosphorylation. Many of the acetylation sites discovered by Choudhary et al. 2 were on proteins in multisubunit complexes. The ...

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...

The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich conditions, producing massive amounts of lactate that accumulate in the tumor ...

In the Gaza Strip, the starvation of children is not a consequence of scarcity; it is the result of sustained ...

Here's how the astronomical phenomenon influences our planet—from the length of our seasons to the way Earth moves through ...

The name is a nod to Ozempic, a prescription medication used primarily for type 2 diabetes that also suppresses appetite.

Over the past half century, researchers have established that birds evolved from dinosaurs: specifically, the theropods, the ...

Liver enzymes that break down alcohol become less efficient with age, causing people to feel the effects of alcohol faster ...

Owners Brad Whiting and Seth O’Malley founded Wilderton Aperitivo in 2019, with a focus on spirit-free botanical cocktails.

Chemistry is often presented as one of the most advanced sciences, yet its day-to-day practice remains surprisingly manual.