This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
AZoLifeSciences on MSN
DeepCodon: A rare-codon–aware AI tool boosts protein expression in E. coli
A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...
Raw sequencing data (FASTQ) Assembled transcriptomes (FASTA) CDS sequences (FASTA) Pre-computed codon usage tables (from CodonW or other tools) The workflow integrates multiple analysis steps into a ...
Living organisms synthesize a staggering variety of proteins by combining 20 amino acids into chains of any length and order. In the past, to expand protein diversity beyond the scope of these 20 ...
To maintain a healthy credit score, it's important to keep your credit utilization rate (CUR) low. The general rule of thumb has been that you don't want your CUR to exceed 30%, but increasingly ...
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