In recessive disorders, such as the three clinically distinct disorders trichothiodystrophy (TTD), xeroderma pigmentosum (XP), and Cockayne syndrome (CS), all of which involve different mutant alleles ...

The pleiotropic effects of six radiation-induced lethal alleles at the albino locus in the mouse include deficiencies of various enzymes and of serum proteins. Closely correlated with the biochemical ...

Viral Epizootic reveals inbreeding depression in a habitually inbreeding mammal: Inbreeding is typically detrimental to fitness. However, some animal populations are reported to inbreed without ...

1. Two small samples in 1952 from a confined population of wild house mice showed the presence of two t-alleles, a recessive lethal, tw1, and a viable with male sterility in homozygotes, tw2. 2. Two ...