At 71 years old, facing a terminal diagnosis, Colorado resident Tom Pringle has one more thing he wants to do before he dies: help other people in similar situations by trying an experimental drug to ...

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS).

In May 2022, The US FDA authorized the use of RADICAVA ORS (edaravone) in an oral formulation for the treatment of ALS.

Early initiation of tofersen (Qalsody) was associated with a numerically slower decline in people with SOD1 amyotrophic lateral sclerosis (ALS) compared with delayed treatment, according to data from ...

FDA cleared the start of a pivotal Phase 3 trial testing pridopidine, an oral therapy for ALS. The study will enroll people with early, rapidly progressive ALS. Earlier subgroup analyses suggested ...

FDA clearance received to start the pivotal, 500-patient, placebo-controlled Phase 3 “PREVAiLS” study of pridopidine in participants with early, rapidly progressive ALS; US recruitment set to begin ...

A simple blood draw may eventually help doctors confirm ALS sooner. If validated in clinical settings, the new method could potentially transform care for patients facing one of medicine’s most ...

Background: Motor neurone disease (MND) presentation is globally heterogenous and data on the clinical phenotype in Sub-Saharan Africa (SSA) is scarce. We sought to address this by describing the ...

Background: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by progressive motor neuron degeneration, leading to severe functional decline and limited ...

RICHMOND, Va. — The VCU Health ALS Clinic raised funds for patient care at its Canvas for a Cure gala held at the Virginia Museum of History and Culture on Saturday night. Dr. Kelly Gwathmey, the ...

In March 2024, Kayla Gonzalez started having an odd sensation behind her right kneecap. At first, she didn’t think much of it. Then, the feeling started to spread. Soon, she had weakness in her calf, ...