gout of foot The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum uric acid ...

Credit: Getty Images. The comparative efficacy of these therapies has been extended to patients with stage 3 chronic kidney disease, a common comorbidity in gout. Allopurinol and febuxostat are ...

What you need to know ### BMJ Learning To obtain accredited continuous professional development points, subscribers to BMJ Learning can complete the full module at The module contains four additional ...

Trial subgroup analyses support the use of either allopurinol or febuxostat in patients with stage 3 CKD and gout. A prespecified analysis of the STOP-GOUT trial revealed that allopurinol has similar ...

August 9, 2010 (Montreal, Quebec) — An observational study of more than 25 000 heart failure patients has shown that a history of gout and/or an acute episode of gout are associated with an increased ...

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Dear Dr. Roach • I got a call from my internist that my blood test showed an elevated uric acid and I would need to start allopurinol for gout. I had been having big-toe pain at night. A nurse friend ...

Matched cohort studies revealed infrequent adverse events (AEs) with either treatment, but the number needed to harm for any AE was more than three times higher with colchicine vs NSAIDs. The ...

In a 10-year propensity-matched cohort study, Irene Tan, MD, of the Einstein Healthcare Network and Jefferson Health in ...

Over the years, gout has grown in clinical complexity. We see many more cases with iatrogenic factors, multiple comorbidities, advanced age and treatment-refractory hyperuricemia and arthritis (Table ...