Basal ganglia are deep grey matter structures in the brain involved in the control of posture and voluntary movements, cognition, behaviour, and motivational states. Several conditions are known to ...

The substantia nigra is a motor nucleus located in the basal ganglia of the midbrain. This brain structure contributes to the body's cognitive and motor functions by sending signals to initiate or ...

This 3D illustration shows color-coded basal ganglia structures. These subcortical brain regions are located beneath the cerebrum's outermost layer of gray matter known as the cerebral cortex. Source: ...

A) Outline of basal ganglia anatomy in a coronal human brain section. B) UMAP clustering of nuclei from 12 brains based on snRNA-seq data. C) Wiring diagram of basal ganglia circuitry. D) Normalized ...

Researchers have applied a chemogenetic tool in macaque monkeys and suppressed the subthalamic nucleus, a part of the basal ganglia circuitry. The chemogenetic suppression induced unstable movements.