Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...

Bacterial ribosomes are essential for protein synthesis, yet they can become stalled during translation when encountering aberrant mRNAs or premature termination signals. To preserve the efficiency of ...

Ribosomes are tiny molecular machines inside all living cells that build proteins, and ribosome biogenesis is the complex, multi-step process by which they are made. During brain development, neural ...

Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...

That's important because nascent peptide folding determines whether drugs would arrest ribosome or not." "This method opens countless avenues for structural and functional studies aimed at ...

Scientists have found that human ribosomes decode mRNA slower than bacteria, with implications for drug development. Scientists at St. Jude Children's Research Hospital revealed that human ribosomes ...

Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published today in Nature Communications. The subtle changes might be enough to alter the binding site of ...

Research by UC Santa Cruz molecular biologist Harry Noller and his collaborators has led to the first direct observations of the mechanism for protein synthesis in living cells. Their new findings on ...

Maximiliane Wieland, Mikael Holm, Emily J. Rundlet, Martino Morici, Timm O. Koller, Tinashe P. Maviza, Domen Pogorevc, Ilya A. Osterman, Rolf Müller, Scott C ...

Cryo-EM structure of the Giardia ribosome reveals a highly compact, GC-rich rRNA with eukaryotic r-proteins. (A) Structure of the Giardia ribosome with all the r-proteins colored (SSU, shades of blue ...