Proposed model for Regulation of BMP Activity by DDR2. After binding collagen, DDR2 alone or together with collagen-binding β1 integrins stabilizes YAP/TAZ nuclear accumulation. This is accomplished ...

This week, we are going to discuss a condition that occurs after trauma and surgery as well as after traumatic injuries to the head, neck and spine. The condition? Heterotopic ossification.

In a new study published on 21 July 2023 by the journal Bone Research, a team of researchers from Johns Hopkins University, using a combination of lineage tracing and single-cell RNA sequencing (scRNA ...

Bone regeneration research has taken a significant leap forward with the discovery of a crucial mechanism that could transform treatments for bone disorders. Scientists have identified how Discoidin ...

A new small molecule could treat and prevent excess bone formation. Fibrodysplasia ossificans progressiva (FOP) is an extremely rare disease estimated to affect about one in 2 million people worldwide ...

Regeneron’s rare disease drug outshone placebo in a phase 2 study, warding off the majority of new bone formation in adults with a disorder that causes the body’s soft tissues to turn into bone. Full ...