Ewing sarcoma is a tumor of the bones and soft tissues that occurs in children and young people. Like all childhood cancers, it is rare—nine to 10 cases per million inhabitants per year—but it is very ...

Melanomas resistant to BRAF inhibitors show increased polyamine biosynthesis, driven by the activation of the oncogene c-Myc. This ultimately leads to increased mitochondrial activity and drug ...

or on the link below. Druggable oncogene-driven non–small cell lung cancer (NSCLC) has led to innovative systemic treatment options, improving patients' outcome. This benefit is not only achieved in ...

DJ-1 might have chaperone activity, which helps to refold proteins in the presence of oxidative stress and other cell stress contiditions. It may in fact sense oxidative signals via oxidation at ...