Glycans can enhance, dampen or redirect protein activity. Glycan modification can alter size, charge and geometry, shield an enzyme from degradation, help a hormone find its receptor or steer an ...

The study of glycan analysis is pivotal in understanding cellular communication, protein functionality and the therapeutic efficacy of glycoproteins. Mass spectrometry techniques have emerged as ...

Glycosylation profoundly affects the efficacy and safety of therapeutic proteins, influencing their biological activity, serum half-life, and immunogenicity. This post-translational modification, ...

N-glycosylation is one of the most common posttranslational modifications encountered on biopharmaceuticals. While the modification is often critical to achieve efficient folding and secretion of the ...

In the future, a little saliva may be enough to detect an incipient cancer. Researchers at the University of Gothenburg have developed an effective way to interpret the changes in sugar molecules that ...

The researchers observed glycan-mediated interactions between Spike and glycans at sites N090, N322, and N546 on ACE2, suggesting that variations in the occupancy or processing of glycans at these ...

There is a growing demand in the biopharmaceutical industry for rapid N-glycosylation profiling of therapeutic antibodies. SCIEX has developed a Fast Glycan Labeling and Analysis Kit for high speed ...

Carbohydrates are ubiquitous. They densely carpet cell surfaces. They are the main component of the extracellular matrix that surrounds cells. They are involved in many aspects of cell-cell ...

Diabody vinorelbine conjugate (DVC) composed of vinorelbine-tartrate conjugated to anti-DNMT1/SHH di-diabody induce ADCC, CDC, AMP and inhibit DNA methylation No significant financial relationships to ...

WASHINGTON, Jan. 28, 2013 /PRNewswire/ -- Waters Corporation today reinforced its commitment to advancing biotherapeutic characterization technology at the Well Characterized Biotechnology ...