CURE

Trodelvy Shows Fewer Side Effects Than Chemotherapy in Some With TNBC

Trodelvy showed fewer severe side effects, such as neutropenia and diarrhea, compared to chemotherapy in untreated TNBC ...
ascopubs.org

Effects of G-CSF on circulating tumor cells (CTC) and CA 27.29 in breast cancer patients

Gauging the response of circulating epithelial tumor cells (CETC) and tumor stem cell subpopulations to therapy of early-stage cancer in the individual patient This is an ASCO Meeting Abstract from ...
ascopubs.org

Effect of rhG-CSF Combined With Decitabine Prophylaxis on Relapse of Patients With High-Risk MRD-Negative AML After HSCT: An Open-Label, Multicenter, Randomized Controlled Trial

First-in-Human Phase I Study of Iadademstat (ORY-1001): A First-in-Class Lysine-Specific Histone Demethylase 1A Inhibitor, in Relapsed or Refractory Acute Myeloid Leukemia We conducted a phase II, ...
The American Journal of Managed Care

CIN Prophylaxis: Treating With G-CSFs

Lee Schwartzberg, MD, FACP: While colony-stimulating factors like G-CSF [granulocyte colony-stimulating factor] have revolutionized the approach to chemotherapy-induced neutropenia [CIN] and febrile ...
JSTOR Daily

G-CSF Induces Membrane Expression of a Myeloperoxidase Glycovariant that Operates as an E-selectin Ligand on Human Myeloid Cells

Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 29 (July 22, 2014), pp. 10696-10701 (6 pages) The host defense response critically depends on the ...
The American Journal of Managed Care

The Long-term Social Value of Granulocyte Colony-Stimulating Factors

Although currently underutilized, granulocyte colony-stimulating factor prophylaxis as supportive cancer care provides substantial value to society. Aligning utilization with clinical guidelines would ...