The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

Hemostasis is a complex system composed of many procoagulant and regulatory pathways. Multiple pathways, such as the intrinsic pathway, platelet activation and the tissue factor pathway, can affect ...

Hemophilia A and B involve deficiencies in coagulation factors VIII and IX, with traditional treatments requiring frequent infusions. Nonfactor therapies, including Hemlibra and rebalancing agents, ...

As people age they become more prone to blood clotting diseases, which can be caused when blood platelets clump together. This clumping can lead to strokes and cardiovascular disease. For decades, ...

Inflammatory bowel disease, in which the immune system attacks the gut, is a painful chronic condition that affects three million Americans. Rates of IBD are rising, and there's currently no cure. IBD ...

Researchers at Oregon Health & Science University have uncovered how a molecule found on certain bacteria may drive blood clotting in sepsis, a life-threatening condition that causes about 8 million ...