Mitotic chromosomal assembly in vertebrates is regulated by condensin I and condensin II, which work cooperatively but have different chromosomal localization profiles and make distinct mechanistic ...
Figure 1: Schematic overview of the process used to derive and apply a gene expression signature of chromosomal instability. Figure 3: Metastatic foci expressed higher levels of the net CIN25 ...
Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply — and can contribute to infertility, pregnancy loss, and ...
In a newly published article in Nature Genetics, researchers from the University of Chicago have identified tumor aneuploidy—an imbalance in the number of chromosomes—as a powerful biomarker ...
Impact of age on efficacy and safety of daratumumab in combination with lenalidomide and dexamethasone (D-Rd) in patients (pts) with transplant-ineligible newly diagnosed multiple myeloma (NDMM): MAIA ...
A new research paper was published in Volume 17, Issue 10 of Aging-US on October 10, 2025, titled "Developmental arrest rate of an embryo cohort correlates with advancing reproductive age, but not ...
Researchers describe how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body's ability to suppress it. The Epstein-Barr virus (EBV) is easily spread through ...
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Chromosomal chaos promotes therapy resistance in leukemia cells and opens up new treatment approaches
Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer ...
A genetic disorder is a condition that occurs as a result of a mutation to DNA. There are several different genetic disorders. Most cells within the body contain the molecule DNA. This molecule ...
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