Christina Applegate got emotional as she detailed her frustrations and fears over a recent multiple sclerosis (MS) flare-up.

Christina Applegate is working on a memoir about her life. "I've watched Saturday Night Live since I was little, which I probably shouldn't have been watching, but I was raised by Nancy [Priddy]," ...

In the flashback photo, a 13-year-old Applegate can be seen wearing a vintage grey patterned sweater and a black beret during ...

Christina Applegate is sharing her truth about going under the knife. During the latest episode of her podcast, the "Dead to Me" alum admitted she had plastic surgery after a "famous" producer ...

Christina Applegate said she lies in bed “screaming” due to the “sharp pains” from her multiple sclerosis (MS). On the Tuesday episode of her “MeSsy” podcast, the “Married… with Children” alum and her ...

Christina Applegate admitted she previously took things for 'granted' before her Multiple Sclerosis diagnosis. Her battle has progressed to the point where she joked she has trouble getting up to go ...

Christina Applegate is having to get used to her new level of athleticism after being diagnosed with multiple sclerosis. Now, that her catch-ups with friends are no longer hiking up hills or playing ...

Christina Applegate and Jamie-Lynn Sigler read some emails from listeners on the latest episode of their podcast MeSsy With Christina Applegate and Jamie-Lynn Sigler, and seized upon one in part ...

"It’s my last awards show as an actor probably, so it’s kind of a big deal." Christina Applegate is opening up on what work she'll pursue in the future amid her battle with multiple sclerosis. In an ...

Christina Applegate's MS diagnosis has impacted her 14-year-old daughter, Sadie, in more ways than she could have ever imagined. During a recent episode of her "MeSsy" podcast with co-host Jamie-Lynn ...