Doctors use molecular responses to monitor the effectiveness of CML treatment. A major molecular response is when the amount of the abnormal BCR–ABL gene in your blood and bone marrow is lowered to ...

Imatinib (Glivec ®) induces major cytogenetic responses in the vast majority of newly diagnosed CML patients. Most of these responses are durable, but a minority of patients progress to accelerated ...

Most studies test for mutations in the kinase domain of the abl gene in chronic myeloid leukemia (CML) using peripheral blood (PB) cells. Frequently, progression of the disease manifests with ...

Chronic myeloid leukemia (CML) is a type of blood cancer that people may also refer to as chronic myelogenous leukemia. Doctors diagnose the stage of CML based on the number of leukemia cells, or ...